ABOUT
HOW EZIUM CAME TO BE
From the creator, Dr. Teena Middleton:
Have you ever had a horse that you just knew had lots of talent but they were always too “something” to achieve their potential? For me, that horse was “MUSIC OF MY HEART." Everyday was something different - too tight, too reactive, too sensitive…..you name it. I tried everything before I discovered the power of chelated magnesium. However, there was no affordable chelated magnesium option that was easy to feed, which was why I invented EZium!
I never intended to go into business, I only wanted a pelleted supplement in my feedroom that soothed my "savage beast." Friends saw how it transformed “MUSIC,” wanted the same results for their horses, and EZium was born. If it worked for “MUSIC,” I know it will work for you.
Take this Quiz to find out!
Feed one (1) enclosed 70 g measuring scoop with ration twice daily or as recommended by your veterinarian or a qualified nutritionist.
Because EZium contains a chelated source of Magnesium, the recommended dose does not provide an excess of Magnesium which can interfere with the absorption of other nutrients or cause diarrhea. The quantity of the highly available source of Magnesium provided by feeding two level scoops of EZium per day has been found to be ideal for most horses. But no horse is the same! So for maximum health and performance benefits, your horse may require slightly more or less. Feel free to contact us to discuss your horse's specific needs.
Most users begin to see an improvement in their horses within two to three weeks. Horses with a severe deficiency have demonstrated better performance within four days.
Remember, Magnesium is not a calming supplement. It simply assists your horse's muscles to relax/recover and his nervous system to respond more normally to stimuli. This recovery process does take a little time.
There is no accepted test for assessing your horse's Magnesium status. Blood levels are poor indicators of your horse's Magnesium status because only 1% of the body's Magnesium is in the blood. Most is in the cells or in the bone where it can't be tested. The best way to diagnose a Magnesium deficiency is by assessing the presence or absence of the symptoms of a deficiency.
Performance Demands
Strenuous exercise places enormous demands on your horse's Magnesium stores. Magnesium is required for the proper function of the enzymes responsible for the generation of cellular energy as well as protein synthesis. In addition, the Magnesium lost in sweat can increase the requirements for this mineral by up to 20%. It is very likely that, without proper supplementation with a bioavailable form of Magnesium, the performance demands of competition will leave your horse deficient in Magnesium.
Stress
1. In response to stress, adrenaline is released. Magnesium is required to produce adrenaline. In order to produce adrenaline, the body pulls Magnesium from its bodily stores, temporarily raising serum levels.
2. In response to adrenaline, Calcium moves into the cells preparing them to "fire now". This pushes Magnesium out, temporarily raising serum levels.
3. In response to elevated serum levels of Magnesium, the kidneys upregulate the capture and excretion of Magnesium to try to restore normal levels. This depletes the body of the Magnesium it needs.
4. Chronic stress depletes the body of Magnesium and causes calcium to accumulate in the tissues. A reduction in the Magnesium/Calcium ratio makes it difficult for the cells to ever relax.
Dietary Antagonists in Feed & Forages
Other compounds in your horse’s feed can negatively impact your horse's ability to absorb the Magnesium naturally contained. For example, Magnesium in most dietary sources as well as most supplements can chemically bond to the fiber in the diet to form insoluble compounds, resulting in the mineral being excreted along with the fiber in the feces. The form of phosphorus in most plants (phytate phosphorus) can bind with Magnesium making it unavailable for absorption. The diagram at left shows the maze of minerals interferences that can also occur. High levels of Calcium in the diet can particularly interfere with the ability to absorb and utilize non-chelated sources of Magnesium because the two minerals share a common carrier in the intestine. Phosphorus combines with non-chelated sources of Magnesium to form insoluble phosphates, preventing the absorption of both minerals.
Disease and Other Factors
While it is obvious that the increased rate of passage that accompanies diarrhea can reduce your horse's opportunity to absorb Magnesium, what is less obvious are the demands placed on your horse's Magnesium reserves by chronic inflammation. Magnesium has a role in reducing inflammation. Low Magnesium concentrations are associated with increased cytokine production and systemic inflammation. Supplemental Magnesium has also been shown to benefit horses impacted by endotoxemia, such as after a colic or bout of laminitis.
Older horses, lactating mares, and growing foals have increased Magnesium demands that often cannot be fulfilled without supplementation.
Mild Deficiency Symptoms
Nervousness and flighty behavior
Muscle cramps and spasms
Resistance to training
Tension and tight back
Hypersensitivity
Inability to focus and relax
Poor tolerance to work
Excessive sweating and increased respiration
Anhidrosis
Increased severity of inflammatory responses
Exacerbation of pain responses
Severe Deficiency Symptoms
Recurrent Exertional Rhabdomylosis (Tying Up)
Muscle cramps and spasms
Lack of muscle coordination with the potential for collapse
Deep, exaggerated, rapid, and labored respiration
Metabolic dysfunction and weight gain
Convulsions
Death due to respiratory failure
Magnesium is involved in over 300 enzymatic reactions, including those that control carbohydrate metabolism, protein synthesis, energy production, and protection against inflammation and free radical damage. Magnesium works in concert with Calcium in muscle contractions and nerve transmissions. Magnesium's role is to facilitate muscle relaxation and to diminish the excitability of the nervous system. Magnesium lowers blood sugar by sensitizing the insulin receptors, resulting in a more normal insulin response. Magnesium supplementation replaces the magnesium depleted during stress and has a role in reducing inflammation.
EZium contains a chelated source of Magnesium called Magnesium Glycinate. Research shows that true metal amino acid chelates such as magnesium glycinate are the most bioavailable, best absorbed, and most retained of all mineral forms currently on the market. The unique ring formation that is characteristic of a true amino acid chelate provides stability and protection during digestion for optimum mineral absorption. Most economically priced supplements contain only inorganic forms of magnesium, such as magnesium oxide or perhaps small amounts of other organic forms of magnesium. The magnesium in EZium is absorbed 4.1 times better than the magnesium in magnesium oxide.
It is not the amount of total magnesium in a supplement that is important. What is important is the amount of magnesium that is in a form the horse can actually absorb.
There is a lot of magnesium in the food the horses eat already. Massive amounts! Magnesium is the third highest mineral in any food. Timothy Hay, for example, has 0.13% magnesium. This means a horse eating a standard 10 pounds of Timothy Hay a day would get 5 grams of Magnesium just from the hay. Unfortunately, most of the magnesium present in hays, grains, and even other Magnesium supplements is not in a form that the animal can absorb.
If you analyze EZium, 3.75% of the total weight of the product is magnesium. Breaking that down per scoop, there is a total of 2,624 mg or 2.624 grams of TOTAL magnesium per scoop. 1.750 grams comes from the 100% bioavailable form of the product.
Calcium's role is to facilitate muscle contraction:
When the muscle cell is triggered, the Calcium channels in the cell membrane open, letting Calcium in. Increases in the Calcium level in the cell triggers the reaction. The Calcium binds to the actin-myosin complex, locking it in a shortened or contracted state. Magnesium's role is to facilitate muscle relaxation:
Once its task is fulfilled, Calcium is ushered out of the cell by the action of Magnesium, releasing the contraction. Magnesium knocks the Calcium from the binding site on the actin-myosin complex, allowing it to relax to the inactive or non-contracted state. The proper Magnesium to Calcium ratio in the cells maintains the cell in a state of relaxation.
Magnesium lowers blood sugar by sensitizing the insulin receptors, resulting in a more normal insulin response.
Magnesium levels increase in the blood following glucose ingestion as it is involved in the action of insulin to clear glucose from the blood. Reduced Magnesium concentrations at the insulin receptor level result in defective enzyme activity. Links between Magnesium deficiency and diabetes have been demonstrated in rats. Magnesium deficiencies have been implicated in Equine Metabolic Syndrome.
Horses with metabolic concerns such as Cushing's Disease, Laminitis, Equine Metabolic Disorder, or Polysaccharide Storage Myopathy (PSSM) require reduced levels of Non-Structural Carbohydrates (sugars and starches) in their diet. High levels of Non-Structural Carbohydrates (NSC) in these horses can create a rapid spike in blood glucose. Most veterinarians and nutritionists recommend that the levels of NSC be below 12% for these horses. Grains can supply as high as 40-60% NSC.
EZium contains less than 6% Non-Structural Carbohydrates. You can feed EZium with confidence knowing that the ingredients in EZium will not contribute significantly to the total NSC in your horses diet.
The gut and the brain are intricately connected. Learn all about it with this quiz!
Please contact us at GetEZium@gmail.com to pause or cancel your subscription at any time. Edits to your payment and billing information as well as shipping address can be made through your client portal. Feel free to contact us with any questions or concerns!